The Concept of Postbiotics

Postbiotic is a term derived from the Greek for ‘post’, meaning after, and ‘bios’, meaning life. Further, the ‘biotic’ family of terms (probiotics, prebiotics,…

The Concept of Postbiotics|690x360

Postbiotic is a term derived from the Greek for ‘post’, meaning after, and ‘bios’,
meaning life. Further, the ‘biotic’ family of terms (probiotics, prebiotics, synbiotics and postbiotics) coalesces around microbes (or their substrates).

Therefore, the term postbiotic appropriately refers to substances derived after the microorganisms are no longer alive, or, in other words, inanimate, dead or inactivated.

The microbes comprising a postbiotic may be inanimate, intact cells or may be structural fragments of microbes, such as cell walls.

Many preparations of postbiotics also retain microbe-produced substances,
such as metabolites, proteins, or peptides, which may contribute to the overall health effect
conferred by a postbiotic, but such components are not essential to a postbiotic.

A postbiotic must be derived from a well-defined microorganism or combination of microorganisms for which genomic sequences are known and prepared using a delineated technological process of biomass production and inactivation, which can be reliably reproduced.

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