Preparation, Stability and In Vitro Antineoplastic Function of Lecithin–Chitosan–Polyethylene Glycol Nanoparticles Loaded with Bioactive Peptides Derived from Phycocyanin

Phycocyanin (PC) is a type of alga-derived protein which exerts the role of light harvesting in Spirulina and Cyanophyta cells. Studies have widely proved that phycocyanin exhibits antineoplastic functions, while investigations on its bioactive peptides remain poorly doc- umented. In previous work, three phycocyanin-derived peptides (PCPs: PCP1-3), which exerted anticancer effects in non-small cell lung cancer (NSCLC) cells, were successfully identified. In consideration of the in vitro...