Effect of Food Allergens on the Duodenal Mucosa Visualized by Probe-Based Confocal Laser Endomicroscopy

Background: Irritable bowel syndrome (IBS) is a chronic condition affecting around 4% of the global population. Despite extensive testing, only half of IBS patients with suspected food allergies receive a definitive diagnosis using current standard tests. Confocal laser endomicroscopy (CLE) provides high-resolution, real-time visualization of the intestinal mucosa and may offer new insights into the relationship between food allergens and IBS. Methods: This prospective study evaluated the...