Effect of Food Matrix and Administration Timing on the Survival of Lactobacillus rhamnosus GG During In Vitro Gastrointestinal Digestion

Probiotics’ potential to enhance gut health is often limited by their poor survival dur- ing gastrointestinal (GI) transit, a challenge influenced by the composition and timing of co-ingested foods. Addressing the lack of dietary guidelines for optimal probiotic adminis- tration, this in vitro study examines how consuming Lactobacillus rhamnosus GG (LGG) with different foods at varying timings affects bacterial survival during simulated digestion. The results showed that simultaneous intake...