Lycium barbarum polysaccharide modulates gut microbiota to alleviate rheumatoid arthritis in a rat model

ARTICLE OPEN Lycium barbarum polysaccharide modulates gut microbiota to alleviate rheumatoid arthritis in a rat model Wenjia Lai 1,4 , Chunyan Wang 2,4 , Renfa Lai3 , Xichun Peng 2 ✉ and Jianming Luo 2 ✉ Rheumatoid arthritis (RA) seriously impairs the quality of life of sufferers. It has been shown that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with medicinal and edible functions, can effectively relieve RA, however, whether this effect is related to gut...