An Extensive Analysis of Artemisia integrifolia Linn. on T2DM: Investigating Glycolipid Metabolism, Metabolic Profiling, and Molecular Docking for Potential Functional Food Applications

Type II diabetes mellitus (T2DM) is characterized by chronic glycolipid metabolic dysregu- lation. This study aimed to investigate the effects and mechanisms of Artemisia integrifolia Linn. (LH) as a functional food in a T2DM rat model. The UPLC-Q-TOF-MS/MS technique was used to identify the components of LH. T2DM was induced in rats via a high-fat/high- sugar diet combined with streptozotocin (STZ, 35 mg/kg, i.p.). The rats were subsequently treated with LH (90 mg/kg, 180 mg/kg) for 15 days....