Dietary inclusion of nitrite-containing frankfurter exacerbates colorectal cancer pathology and alters metabolism in APCmin mice

ARTICLE OPEN Dietary inclusion of nitrite-containing frankfurter exacerbates colorectal cancer pathology and alters metabolism in APCmin mice William Crowe 1 , Xiaobei Pan 1 , James Mackle 1 , Adam Harris 1 , Gary Hardiman 1 , Christopher T. Elliott 1,2 and Brian D. Green 1 ✉ Colorectal cancer (CRC) is the second most prevelant malignancy in Europe and diet is an important modifiable risk factor. Processed meat consumption, including meats with preservative salts such as sodium nitrite, have...