Oral Sodium Hyaluronate Moisturizes Skin in Healthy Adults: An 8-Week, Randomized, Double-Blinded, Placebo-Controlled Study

Objective: Few studies have evaluated the effect of oral sodium hyaluronate (SH) ingestion on the moisture content of the superficial stratum corneum. This study aimed to assess whether oral SH ingestion improves the moisture content of the upper layer of the stratum corneum, which is susceptible to changes in environmental humidity, using the Skicon 200EX. Design: Ran- domized, double-blind, placebo-controlled, parallel-group study. Partici- pants: One hundred healthy Japanese men and women...