Metabolic changes in response to varying whole-grain wheat and rye intake

ARTICLE OPEN Metabolic changes in response to varying whole-grain wheat and rye intake Ville M. Koistinen 1,2 ✉, Sumanto Haldar 3 , Marjo Tuomainen 2 , Marko Lehtonen4 , Anton Klåvus2 , John Draper5 , Amanda Lloyd 5 , Manfred Beckmann5 , Wendy Bal6 , Alastair B. Ross7 , Kirsten Brandt 6 , Lee Fawcett 8 , Chris Seal 6,10 and Kati Hanhineva1,2,9,10 Epidemiological studies have shown associations between whole-grain intake and lowered disease risk. A sufficient level of whole- grain intake to...