Cyclocarya paliurus ethanol leaf extracts protect against diabetic cardiomyopathy in dbdb mice via regulating PI3KAktNF-B

Background: Diabetic cardiomyopathy (DCM) is a serious complication of diabetes that can lead to sig- nificant mortality. Cyclocarya paliurus is a tree, the leaves of which are often utilized to prevent and treat diabetes mellitus. Whether C. paliurus leaves can prevent or treat DCM, however, it remains to be formally assessed. The present study was therefore designed to assess the ability of C. paliurus to protect against DCM in db/db mice. Methods: Male wild-type (WT) and db/db mice were...