Carica pubescens fruit juice improved superoxide dismutase, triglyceride and high-density lipoprotein levels in type 2 diabetes mellitus Wistar rats

Insulin resistance and insulin deficiency in type 2 diabetes mellitus (T2DM) may increase reactive oxygen species (ROS) production, which can exacerbate pancreatic β-cell. Insulin resistance and insulin deficiency may also reduce lipoprotein lipase (LPL) activity, increase triglycerides (TG) levels and decrease high-density lipoprotein (HDL) levels. This condition could lead to cardiovascular complications. Flavonoids, such as rutin, might be able to improve insulin resistance and increase...