Supramolecular Co-Assembled Fmoc-FRGDFHyaluronic Acid Hydrogel for Quercetin Delivery: Multifunctional Bioactive Platform

Background: During food processing and storage, traditional protein-based delivery systems encounter significant challenges in maintaining the structural and functional in- tegrity of bioactive compounds, primarily due to their temporal instability. Methods: In this study, a nanocomposite hydrogel was prepared through the co-assembly of a self- assembling peptide, 9-Fluorenylmethoxycarbonyl-phenylalanine-arginine-glycine-aspartic acid-phenylalanine (Fmoc-FRGDF), and hyaluronic acid (HA). The...