Polyherbal formulation as an anti-atherosclerosis agent by inhibiting foam cell formation and TNF- expression in a hypercholesterolemic mice model

Atherosclerosis is a progressive inflammatory disease characterized by lipid accumulation in arterial walls. This study investigates the potential of a polyherbal formulation as an anti-atherosclerosis and anti-inflammatory agent in a hyperlipidemic mice model. An in vitro and in vivo observational experimental design was employed, using a randomized post-test control group design with twenty-five hyperlipidemic mice. The hyperlipidemia model was induced by a high-fat diet of 10% beef fat and...