Stronger gut microbiome modulatory effects by postbiotics than probiotics in a mouse colitis model

ARTICLE OPEN Stronger gut microbiome modulatory effects by postbiotics than probiotics in a mouse colitis model Tao Zhang 1,2,3,4 , Weiqin Zhang 1,2,3,4 , Cuijiao Feng 1,2,3 , Lai-Yu Kwok1,2,3 , Qiuwen He 1,2,3 ✉ and Zhihong Sun 1,2,3 ✉ Probiotics are increasingly used as adjunctive therapy to manage gastrointestinal diseases, such as ulcerative colitis. However, probiotic use has posed some safety concerns. Thus, postbiotics are proposed as alternatives to probiotics in clinical applications....