Pentadecanoic acid promotes basal and insulin-stimulated glucose uptake in C2C12 myotubes

Background: Saturated fatty acids (SFAs) generally have been thought to worsen insulin-resistance and increase the risk of developing type 2 diabetes mellitus (T2DM). Recently, accumulating evidence has revealed that SFAs are not a single homogeneous group, instead different SFAs are associated with T2DM in opposing directions. Pentadecanoic acid (C15:0, PA) is directly correlated with dairy products, and a negative associa- tion between circulating PA and metabolic disease risk was observed...