Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling

ARTICLE OPEN Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling Brigitte M. González Olmo1,2 , Menaz N. Bettes2 , James W. DeMarsh 2 , Fangli Zhao3 , Candice Askwith3 and Ruth M. Barrientos 2,3,4,5 ✉ More Americans are consuming diets higher in saturated fats and refined sugars than ever before. These trends could have serious consequences for the older population because high-fat diet (HFD) consumption, known to induce...