Lycium barbarum polysaccharide (LBP) inhibits palmitic acid (PA)-induced MC3T3-E1 cell apoptosis by regulating miR-200b-3pChrdl1PPAR

Background: Obesity is closely related to osteoporosis. Lycium barbarum polysaccharides (LBPs) have an- ti-osteoporosis activity. Objective: This study aimed to explore the role of LBPs in palmitic acid (PA)-induced osteoblast apoptosis. Methods: The microarray data set GSE37676 was downloaded from Gene Expression Ominibus (GEO) data- base. Top 300 differentially expressed genes (DEGs) were used to construct a protein–protein interaction (PPI) network based on STRING database, and significant...