Antidiabetic effects of a lipophilic extract obtained from flowers of Wisteria sinensis by activating AktGLUT4 and AktGSK3

Background: Type 2 diabetes mellitus is primarily caused by insulin resistance (IR) in insulin-sensitive tissues, including liver, white adipose tissues (WAT), and skeletal muscles. Discovering nutritious foods with antidi- abetic effects is of great significance. Numerous published reports indicated that protein kinase B (Akt) and glucose transporter 4 (GLUT4) play crucial roles in ameliorating IR and diabetic symptoms. Objective: In the present study, antidiabetic effects and the potential...