Tryptophan Metabolism and Gut Microbiota

Background: Tryptophan metabolites such as serotonin, kynurenine, or ky- nurenic acids are considered to be the most important metabolites of gut mi- crobiota. We wanted to know about changes in tryptophan metabolites in various diseases in which the etiology gut microbiota are considered to par- ticipate. Methods: Ultra-high speed liquid chromatography/mass spectros- copy (LC/MS) has been used to analyze simultaneously all the tryptophan metabolites, which we have explored for the first time...