White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL6 mice

ARTICLE OPEN White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice Xiaoqiang Wang 1 , Desiree Ha 1 , Ryohei Yoshitake 1 and Shiuan Chen 1 ✉ White button mushroom (WBM) is a common edible mushroom consumed in the United States and many European and Asia- Pacific countries. We previously reported that dietary WBM antagonized dihydrotestosterone (DHT)-induced androgen receptor (AR) activation and reduced myeloid-derived...