Rational design of alcoholic fermentation targeting extracellular carbon

BRIEF COMMUNICATION OPEN Rational design of alcoholic fermentation targeting extracellular carbon Daisuke Watanabe 1 ✉, Mikiya Kawashima1 , Naoya Yoshioka1 , Yukiko Sugimoto 1 and Hiroshi Takagi 1 Breeding yeast strains for industrial alcoholic fermentation requires laborious screening due to the lack of in vivo modification strategies. Here we show that quiescence-specific cell wall thickening via synthesis of a major component, 1,3-β-glucan, critically antagonizes cellular fermentation...