Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion

ARTICLE OPEN Identification of a highly stable bioactive 3-hydroxyproline- containing tripeptide in human blood after collagen hydrolysate ingestion Yuki Taga 1 ✉, Yu Iwasaki 2 , Chisa Tometsuka 1 , Noriko Funato 3 , Yasutaka Shigemura 2 , Masashi Kusubata 1 and Kazunori Mizuno 1 There are increasing reports demonstrating high bioavailability of 4-hydroxyproline (4Hyp)-containing oligopeptides after oral ingestion of collagen hydrolysate and their bioactivity. In contrast, no study...