Apoptosis induction activity of polysaccharide from

Background: Lentinus edodes is a medicinal mushroom widely used in Asian countries for protecting people against some types of cancer and other diseases. Objective: The objective of the present study was to investigate the direct antiproliferation activity and the antitumor mechanisms of water-extracted polysaccharide (WEP1) purified from L. edodes in H22 cells and H22-bearing mice. Design: The extraction, isolation, purification, and structure determination of the water-soluted L. edodes...