Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent What Is New on the Horizon

Hydroxytyrosol (HXT), a phenolic compound from olive, shows great potential as a neu- roprotective agent and a translational target for claim-ready nutrition and food products. Human studies increasingly report benefits for vascular function, inflammatory tone, and early cognitive/psychomotor outcomes, consistent with engagement of redox and sig- nalling pathways (Keap1–Nrf2–ARE, PI3K/Akt–ERK, and AMPK–SIRT1–PGC-1α). HXT is rapidly absorbed and likely reaches the brain, acting on endothelial...